- Peer reviewed papers
(2021)
- Cigdem S, Saito S, Nishikata D, Nagata K, Okuwaki M.
SET-Nup214 and MLL cooperatively regulate the promoter activity of the
HoxA10 gene. Genes Cells 2021 In press
-
- Mogi-Hirawake, H., Nhan NTT., Okuwaki M.
G-patch domain-containing protein 4 localizes to both the nucleoli and
Cajal bodies and regulates cell growth and nucleolar structure. Biochem. Biophy.Res. Commun.2021Jun 25;559:99-105. doi: 10.1016/j.bbrc.2021.04.026.
- (2020)
- Okuwaki M, Saito S, Hirawake-Mogi H, Nagata K.
The interaction between nucleophosmin/NPM1 and the large ribosomal subunit
precursors contribute to maintaining the nucleolar structure
Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118879. doi: 10.1016/j.bbamcr.2020.118879.
- Okuwaki M, Saotome-Nakamura A, Yoshimura M, Saito S, Hirawake-Mogi H, Sekiya
T, Nagata K.
RNA-recognition motifs and glycine and arginine-rich region cooperatively
regulate the nucleolar localization of nucleolin
J Biochem. 2021 Feb 6;169(1):87-100. doi: 10.1093/jb/mvaa095.
- (2019)
- Genoveso MJ, Hisaoka M, Komatsu T, Wodrich H, Nagata K, Okuwaki M.
Formation of adenovirus DNA replication compartments and viral DNA accumulation
sites by host chromatin regulatory proteins including NPM1.
FEBS J. 2020 Jan;287(1):205-217. doi: 10.1111/febs.15027. Epub 2019 Aug
9.
- (2018)
- Abe M., Lin J., Nagata K., Okuwaki M.
Selective regulation of the Interferon gamma inducible genes. FEBS Letters,
592; 244-255 (2018)
- (2017)
- Ueshima, S., Nagata, K., Okuwaki M.
Internal associations of the acidic region of upstream binding factor control
its nucleolar localization. Mol. Cell. Biol., 37(22). pii: e00218-17 (2017
)
- Saito S., Yokokawa T., Iizuka G., Cigdem S., Okuwaki M ., Nagata K.
Function of Nup98 subtypes and their fusion proteins, Nup98-TopIIβ and
Nup98-SETBP1 in nuclear-cytoplasmic transport. Biochem. Biophys. Res. Commun.,
487(1); 96-102 (2017)
- Lin J., Kato M., Nagata K., and Okuwaki M.
Efficient DNA binding of NF-κB requires the chaperone-like function of
NPM1. Nucl. Acids Res. 45(7);3707-3723 (2017)
- Minakuchi M., Sugiyama K., Kato Y., Naito T., Okuwaki M. , Kawaguchi A.,
and Nagata K.
Pre-mRNA processing factor Prp18 is a stimulatory factor of influenza virus
RNA synthesis and possesses the NP chaperone activity. J. Virol. 91; e01398-16
(2017)
- Sato T., Higuchi Y., Shibagaki Y. , Hattori S.
Phosphoproteomic Analysis Identifies Signaling Pathways Regulated by Curcumin
in Human Colon Cancer Cells.Anticancer Res. 2017 Sep;37(9):4789-4798.
- Shirakabe K., Omura T., Shibagaki Y ., Mihara E., Homma K., Kato Y., Yoshimura
A., Murakami Y., Takagi J., Hattori S., Ogawa Y.
Mechanistic insights into ectodomain shedding: susceptibility of CADM1
adhesion molecule is determined by alternative splicing and O-glycosylation.
Sci Rep. 2017 Apr 10;7:46174. doi: 10.1038/srep46174.
- (2016)
- Lin J., Hisaoka M., Nagata K., and Okuwaki M.
Functional characterization and efficient detection of Nucleophosmin/NPM1
oligomers. Biochem. Biophys. Res. Commun., 480, 702-708 (2016)
- Komatsu T., Robinson DR., Hisaoka M., Ueshima S., Okuwaki M ., Nagata K.,
Wodrich H.
Tracking adenovirus genomes identifies morphologically distinct late DNA
replication compartments. Traffic, 17, 1168-1180 (2016)
- Okuwaki M. , Abe M., Hisaoka M., and Nagata K.
Regulation of cellular dynamics and chromosomal binding site preference
of linker histones H1.0 and H1.X. Mol. Cell. Biol., 36, 2681-2696 (2016)
- Saito S., Cigdem S., Okuwaki M. , and Nagata K.
Leukemia-associated Nup214-fusion proteins disturb XPO1-mediated nuclear-cytoplasmic
transport pathway and thereby NF-κB signaling pathway, Mol. Cell. Biol.,
36, 1820-35 (2016)
- Ohtomo H., Akashi S., Moriwaki Y., Okuwaki M ., Osakabe A., Nagata K.,
Kurumizaka H, Nishimura Y.
C-terminal acidic domain of histone chaperone human NAP1 is an efficient
binding assistant for histone H2A-H2B, but not H3-H4, Genes Cells, 21,
252-263 (2016)
- Minegishi Y, Sheng X, Yoshitake K, Sergeev Y, Iejima D, Shibagaki Y , Monma
N, Ikeo K, Furuno M, Zhuang W, Liu Y, Rong W, Hattori S, Iwata T.
CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex
Instability. Sci Rep. 2016 Sep 20;6:33742. doi: 10.1038/srep33742.
- Sato T, Ishii J, Ota Y, Sasaki E, Shibagaki Y , Hattori S.
Mammalian target of rapamycin (mTOR) complex 2 regulates filamin A-dependent
focal adhesion dynamics and cell migration. Genes Cells. 2016 Jun;21(6):579-93.
doi: 10.1111/gtc.12366. Epub 2016 Apr 5.
- Yamada H, Tsutsumi K, Nakazawa Y, Shibagaki Y , Hattori S, Ohta Y.
Src Family Tyrosine Kinase Signaling Regulates FilGAP through Association
with RBM10. PLoS One. 2016 Jan 11;11(1):e0146593. doi: 10.1371/journal.pone.0146593.
eCollection 2016.
- (2015)
- Sugiyama K., Kawaguchi A., . Okuwaki M , Nagata K.
pp32 and APRIL are host cell-derived regulators of influenza virus RNA
synthesis from cRNA, eLife, e08939 (2015)
- Matsunaga A, Harita Y, S hibagaki Y , Shimizu N, Shibuya K, Ono H, Kato
H, Sekine T, Sakamoto N, Igarashi T, Hattori S.
Identification of 4-Trimethylaminobutyraldehyde Dehydrogenase (TMABA-DH)
as a Candidate Serum Autoantibody Target for Kawasaki Disease. PLoS One.
2015 May 26;10(5):e0128189. doi: 10.1371/journal.pone.0128189. eCollection
2015.
- (2014)
- Murano K., Okuwaki M. , Momose F., Kumakura M., Ueshima S., Newbold R.,
Nagata K.
Reconstitution of human rRNA gene transcription in mouse cells by complete
SL1 complex, J. Cell Sci., 127: 3309-3319 (2014)
- Ueshima S., Nagata K., Okuwaki M.
Upstream binding factor-dependent and pre-rRNA transcription-independent
association of pre-rRNA processing factors with rRNA gene. Biochem. Biophys.
Res. Commun. 443(1): 22-27 (2014)
- Hisaoka M., Nagata K., Okuwaki M.
Intrinsically disordered regions of nucleophosmin/B23 regulate its RNA
binding activity through their inter- and intra-molecular association.
Nucl. Acids Res. 42(2):1180-95 (2014)
- Sato T, Akasu H, Shimono W, Matsu C, Fujiwara Y, Shibagaki Y , Heard JJ,
Tamanoi F, Hattori S.
Rheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase,
and dihydroorotase) protein in a GTP- and effector domain-dependent manner
and influences its cellular localization and carbamoyl-phosphate synthetase
(CPSase) activity. J Biol Chem. 2015 Jan 9;290(2):1096-105. doi: 10.1074/jbc.M114.592402.
Epub 2014 Nov 24.
- Suzuki H, Shibagaki Y , Hattori S, Matsuoka M.
Nuclear TDP-43 causes neuronal toxicity by escaping from the inhibitory
regulation by hnRNPs. Hum Mol Genet. 2015 Mar 15;24(6):1513-27. doi: 10.1093/hmg/ddu563.
Epub 2014 Nov 6.
- Otsuka H, Gotoh Y, Komeno T, Ono T, Kawasaki Y, Iida N, Shibagaki Y , Hattori
S, Tomatsu M, Akiyama H, Tashiro F.
Aralin, a type II ribosome-inactivating protein from Aralia elata, exhibits
selective anticancer activity through the processed form of a 110-kDa high-density
lipoprotein-binding protein: a promising anticancer drug. iochem Biophys
Res Commun. 2014 Oct 10;453(1):117-23. doi: 10.1016/j.bbrc.2014.09.067.
Epub 2014 Sep 26.
- Shibagaki Y , Ikuta N, Iguchi S, Takaki K, Watanabe S, Kaihotsu M, Masuda
C, Maeyama K, Mizumoto K, Hattori S.
An efficient screening system for influenza virus cap-dependent endonuclease
inhibitors. J Virol Methods. 2014 Jun;202:8-14. doi: 10.1016/j.jviromet.2014.02.005.
Epub 2014 Mar 11.
- Shiheido H, Aoyama T, Takahashi H, Hanaoka K, Abe T, Nishida E, Chen C,
Koga O, Hikida M, Shibagaki Y , Morita A, Nikawa T, Hattori S, Watanabe
T, Shimizu J.
Novel CD3-specific antibody induces immunosuppression via impaired phosphorylation
of LAT and PLCγ1 following T-cell stimulation. Eur J Immunol. 2014 Jun;44(6):1770-80.
doi: 10.1002/eji.201344146. Epub 2014 Apr 10.
- Iida N , Fujita M, Miyazawa K, Kobayashi M, Hattori S.
Proteomic identification of p38 MAP kinase substrates using in vitro phosphorylation.
Electrophoresis. 2014 Feb;35(4):554-62. doi: 10.1002/elps.201300392. Epub
2013 Nov 29.
- (2013)
- Komaki-Yasuda K., Okuwaki M. , Nagata K., Kawazu S., Kano S.
Identification of a novel and unique transcription factor in the intraerythrocytic
stage of Plasmodium falciparum. PLoS One. 8(9):e74701 (2013)
- Minegishi Y, Shibagaki Y , Mizutani A, Fujita K, Tezuka T, Kinoshita M,
Kuroda M, Hattori S, Gotoh N.
Adaptor protein complex of FRS2β and CIN85/CD2AP provides a novel mechanism
for ErbB2/HER2 protein downregulation. Cancer Sci. 2013 Mar;104(3):345-52.
doi: 10.1111/cas.12086. Epub 2013 Feb 8
- (2012)
- Samad, MA., Komatsu T., Okuwaki M. , Nagata, K.
B23/Nucleophosmin is involved in regulation of adenovirus chromatin structure
at late infection stages, but not in virus replication and transcription.
J. Gen. Virol. 93(Pt6): 1328-38 (2012)
- Okuwaki M. , Sumi A., Hisaoka M., Saotome-Nakamura A., Akashi S., Nishimura
Y., Nagata K.
Function of homo- and hetero-oligomers of human nucleoplasmin/nucleophosmin
family proteins NPM1, NPM2 and NPM3 during sperm chromatin remodeling.
Nucl. Acids Res. 40(11):4861-78 (2012)
- Koyama N, Tokura Y, Münch D, Sahl HG, Schneider T, Shibagaki Y , Ikeda
H, Tomoda H.
The nonantibiotic small molecule cyslabdan enhances the potency of β-lactams
against MRSA by inhibiting pentaglycine interpeptide bridge synthesis.
PLoS One. 2012;7(11):e48981. doi: 10.1371/journal.pone.0048981. Epub 2012
Nov 6.
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