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| 業績（2016〜2022） |
【受賞】
1. Takanori Asakura. Microbiology, Tuberculosis, and Pulmonary Infections - Abstract Scholarship. MUC5B-Dominated Mucus Hyperproduction in the Bronchiolectatic Airway of Non-Cystic Fibrosis Bronchiectasis (NCFB). American Thoracic Society International Conference 2022. May 2022.
2. Takanori Asakura. JRS Young Scientist Award. Clinical phenotypes of bronchiectasis with NTM pulmonary disease: The story in Japan. The 25th Congress of the Asian Pacific Society of Respirology (APSR). Nov. 2021.
【原著】
1. Kato T, Asakura T, Edwards CE, Dang H, Mikami Y, Okuda K, Chen G, Sun L, Gilmore RC, Hawkins P, De la Cruz G, Cooley MR, Bailey AB, Hewitt SM, Chertow DS, Borczuk AC, Salvatore S, Martinez FJ, Thorne LB, Askin FB, Ehre C, Randell SH, O'Neal WK, Baric RS, Boucher RC; NIH COVID-19 Autopsy Consortium. Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease. Am J Respir Crit Care Med. 2022 Jul 11. doi: 10.1164/rccm.202111-2606OC.
2. Tanaka H, Asakura T, Suzuki S, Okamori S, Kusumoto T, Ogawa T, Uno S, Morita A, Lee H, Namkoong H, Kamata H, Sato Y, Uwamino Y, Nishimura T, Ishii M, Fukunaga K, Hasegawa N. Osteoporosis in nontuberculous mycobacterial pulmonary disease: a cross-sectional study. BMC Pulm Med. 2022; 22(1): 202.
3. McElvaney OF, Asakura T, Meinig SL, Torres-Castillo JL, Hagan RS, Gabillard-Lefort C, Murphy MP, Thorne LB, Borczuk A, Reeves EP, Zumwalt RE, Mikami Y, Carroll TP, Okuda K, Hogan G, McElvaney OJ, Clarke J, McEvoy NL, Mallon PW, McCarthy C, Curley G, Wolfgang MC, Boucher RC, McElvaney NG. Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications. EBioMedicine. 2022; 77: 103894.
4. Tanaka H, Asakura T, Kikuchi J, Ishii M, Namkoong H, Kaneko Y, Fukunaga K, Hasegawa N. Development of Rheumatoid Arthritis in Cavitary Mycobacterium avium Pulmonary Disease: A Case Report of Successful Treatment with CTLA4-Ig (Abatacept). Infect Drug Resist. 2022; 15: 91-97.
5. COVID-19 Host Genetics Initiative (Collaborators: Asakura T, Suzuki Y, et al.). Mapping the human genetic architecture of COVID-19. Nature. 2021; 600(7889): 472-477.
6. Tanaka H, Lee H, Morita A, Namkoong H, Chubachi S, Kabata H, Kamata H, Ishii M, Hasegawa N, Harada N, Ueda T, Ueda S, Ishiguro T, Arimura K, Saito F, Yoshiyama T, Nakano Y, Mutoh Y, Suzuki Y, Murakami K, Okada Y, Koike R, Kitagawa Y, Tokunaga K, Kimura A, Imoto S, Miyano S, Ogawa S, Kanai T, Fukunaga K; Japan COVID-19 Task Force. Clinical Characteristics of Patients with Coronavirus Disease (COVID-19): Preliminary Baseline Report of Japan COVID-19 Task Force, a Nationwide Consortium to Investigate Host Genetics of COVID-19. Int J Infect Dis. 2021; 113: 74-81.
8. Nakagawara K, Namkoong H, Terai H, Masaki K, Tanosaki T, Shimamoto K, Lee H, Tanaka H, Okamori S, Kabata H, Chubachi S, Ikemura S, Kamata H, Yasuda H, Kawada I, Ishii M, Ishibashi Y, Harada S, Fujita T, Ito D, Bun S, Tabuchi H, Kanzaki S, Shimizu E, Fukuda K, Yamagami J, Kobayashi K, Hirano T, Inoue T, Kagyo J, Shiomi T, Ohgino K, Sayama K, Otsuka K, Miyao N, Odani T, Oyamada Y, Masuzawa K, Nakayama S, Suzuki Y, Baba R, Nakachi I, Kuwahara N, Ishiguro T, Mashimo S, Minematsu N, Ueda S, Manabe T, Funatsu Y, Koh H, Yoshiyama T, Saito F, Ishioka K, Takahashi S, Nakamura M, Goto A, Harada N, Kusaka Y, Nakano Y, Nishio K, Tateno H, Edahiro R, Takeda Y, Kumanogoh A, Kodama N, Okamoto M, Umeda A, Hagimura K, Sato T, Miyazaki N, Takemura R, Sato Y, Takebayashi T, Nakahara J, Mimura M, Ogawa K, Shimmura S, Negishi K, Tsubota K, Amagai M, Goto R, Ibuka Y, Hasegawa N, Kitagawa Y, Kanai T, Fukunaga K. Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol. BMJ Open Respir Res. 2021; 8(1): e001015.
9. Egawa T, Masuzawa K, Nakayama S, Maeda I, Tsunematsu S, Suzuki Y, Suzuki Y. Synchronous Primary Lung Adenocarcinoma and Hepatocellular Carcinoma Successfully Treated with a Combination of Atezolizumab, Bevacizumab, Carboplatin, and Paclitaxel. Intern Med. 2021; 60(20): 3273-3277.
10. Namkoong H, Omae Y, Asakura T, Ishii M, Suzuki S, Morimoto K, Kawai Y, Emoto K, Oler AJ, Szymanski EP, Yoshida M, Matsuda S, Yagi K, Hase I, Nishimura T, Sasaki Y, Asami T, Shiomi T, Matsubara H, Shimada H, Hamamoto J, Jhun BW, Kim SY, Huh HJ, Won HH, Ato M, Kosaki K, Betsuyaku T, Fukunaga K, Kurashima A, Tettelin H, Yanai H, Mahasirimongkol S, Olivier KN, Hoshino Y, Koh WJ, Holland SM, Tokunaga K, Hasegawa N; Nontuberculous Mycobacteriosis and Bronchiectasis - Japan Research Consortium (NTM-JRC). Genome-wide association study in patients with pulmonary Mycobacterium avium complex disease. Eur Respir J. 2021; 58(2): 1902269.
11. Ogawa T, Asakura T, Suzuki S, Okamori S, Kusumoto T, Sato Y, Namkoong H, Kamata H, Ishii M, Fukunaga K, Hasegawa N. Longitudinal validity and prognostic significance of the St George's Respiratory Questionnaire in Mycobacterium avium complex pulmonary disease. Respir Med. 2021; 185: 106515.
12. Terai H, Hamamoto J, Emoto K, Masuda T, Manabe T, Kuronuma S, Kobayashi K, Masuzawa K, Ikemura S, Nakayama S, Kawada I, Suzuki Y, Takeuchi O, Suzuki Y, Ohtsuki S, Yasuda H, Soejima K, Fukunaga K. SHOC2 Is a Critical Modulator of Sensitivity to EGFR-TKIs in Non-Small Cell Lung Cancer Cells. Mol Cancer Res. 2021; 19(2): 317-328.
13. Tanosaki T, Kabata H, Matsusaka M, Miyata J, Masaki K, Mochimaru T, Okuzumi S, Kuwae M, Watanabe R, Suzuki Y, Sayama K, Izuhara K, Asano K, Fukunaga K. Clinical characteristics of patients with not well-controlled severe asthma in Japan: Analysis of the Keio Severe Asthma Research Program in Japanese population (KEIO-SARP) registry. Allergol Int. 2021; 70(1): 61-67.
14. Sunata K, Terai H, Seki H, Mitsuhashi M, Kagoshima Y, Nakayama S, Wakabayashi K, Muraoka K, Suzuki Y, Suzuki Y. Analysis of clinical outcomes in elderly patients with impaired swallowing function. PLoS One. 2020; 15(9): e0239440.
15. Hou YJ, Okuda K, Edwards CE, Martinez DR, Asakura T, Dinnon KH 3rd, Kato T, Lee RE, Yount BL, Mascenik TM, Chen G, Olivier KN, Ghio A, Tse LV, Leist SR, Gralinski LE, Schäfer A, Dang H, Gilmore R, Nakano S, Sun L, Fulcher ML, Livraghi-Butrico A, Nicely NI, Cameron M, Cameron C, Kelvin DJ, de Silva A, Margolis DM, Markmann A, Bartelt L, Zumwalt R, Martinez FJ, Salvatore SP, Borczuk A, Tata PR, Sontake V, Kimple A, Jaspers I, O'Neal WK, Randell SH, Boucher RC, Baric RS. SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract. Cell. 2020; 182(2):429-446.e14.
16. Masaki K, Miyata J, Kamatani T, Tanosaki T, Mochimaru T, Kabata H, Suzuki Y, Asano K, Betsuyaku T, Fukunaga K. Risk factors for poor adherence to inhaled corticosteroid therapy in patients with moderate to severe asthma. Asian Pac J Allergy Immunol. 2020. doi: 10.12932/AP-311219-0731.
17. Ishii M, Terai H, Kabata H, Masaki K, Chubachi S, Tateno H, Nakamura M, Nishio K, Koh H, Watanabe R, Ueda S, Terashima T, Suzuki Y, Yagi K, Miyao N, Minematsu N, Inoue T, Nakachi I, Namkoong H, Okamori S, Ikemura S, Kamata H, Yasuda H, Kawada I, Hasegawa N, Fukunaga K, Keio COVID-19 Research Consortium and the Keio Donner Project Team. Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: A multicenter retrospective study. J Infect. 2020; 81(5): e3-e5.
18. Ueda S, Fukunaga K, Takihara T, Shiraishi Y, Oguma T, Shiomi T, Suzuki Y, Ishii M, Sayama K, Kagawa S, Hirai H, Nagata K, Nakamura M, Miyasho T, Betsuyaku T, Asano K. Deficiency of CRTH2, a Prostaglandin D2 Receptor, Aggravates Bleomycin-induced Pulmonary Inflammation and Fibrosis. Am J Respir Cell Mol Biol. 2019; 60(3): 289-298.
19. Mochimaru T, Ueda S, Suzuki Y, Asano K, Fukunaga K. Neutrophil-to-lymphocyte ratio as a novel independent predictor of severe exacerbation in patients with asthma. Ann Allergy Asthma Immunol. 2019; 122(3): 337-339.e1.
20. Mochimaru T, Fukunaga K, Miyata J, Matsusaka M, Masaki K, Kabata H, Ueda S, Suzuki Y, Goto T, Urabe D, Inoue M, Isobe Y, Arita M, Betsuyaku T 12-OH-17,18-Epoxyeicosatetraenoic acid alleviates eosinophilic airway inflammation in murine lungs. Allergy. 2018; 73(2): 369-378.
21. Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T. Characteristics of severe asthma with fungal sensitization. Ann Allergy Asthma Immunol. 2017; 119(3): 253-257.
22. 野中葉月, 篠崎公一, 平岡聖樹, 斎藤太寿, 小林義和, 斎藤雅俊, 鈴木幸男. バンコマイシンの施設の患者特異性を考慮した母集団薬物動態モデルの検討. TDM研究. 2017; 34(2): 51-59.
23. 栗林杏子, 西村宏平, 篠崎公一, 斎藤太寿, 小林義和, 齋藤雅俊, 平岡理佳, 竹下啓, 鈴木幸男. 母集団薬物動態モデル6種のパラメータ代表値によるバンコマイシン血中濃度予測性の現状. TDM研究. 2015; 32(3): 109-115.
24. 藤岡貴光, 齋藤雅俊, 小林義和, 斎藤太寿, 伊東崇仁, 阿部真也, 町田美香, 柴田壮一, 井上岳, 月村泰規, 千葉一裕, 厚田幸一郎, 松原肇. 医師との協働に基づき作成したプロトコールの導入とその評価 整形外科領域の疼痛管理に対する薬剤師の処方支援. 医療薬学. 2014; 40(7): 396-401.
25. 小林義和, 齋藤雅俊, 藤野玲子, 西真由美, 柴田壮一, 厚田幸一郎. 病棟薬剤業務日誌システムの構築. 医薬品情報学. 2013; 15(2): 90-96.
26. 松原慎, 篠崎公一, 渡部智之, 西村宏平, 江川由希子, 梶野哲, 谷貴美恵, 甲斐幹夫, 月居茉莉子, 齋藤雅俊, 小林義和, 鈴木幸男, 竹下啓, 平岡理佳. TDM、薬物動態学および薬力学に基づく適正抗菌薬療法のための臨床分離株の最小発育阻止濃度の調査. TDM研究. 2012; 29(4): 89-97.
27. 小林義和, 田中麻衣, 高野照子, 増渕幸二, 柴田壮一, 鈴木幸男, 厚田幸一郎. 院内抗菌薬使用ガイドブックの作成とその評価. 医薬品情報学. 2011; 13(1): 2-7.
【総説・解説】
1. 朝倉崇徳: 研究トピックスオーバービュー A．気道上皮. 気管支拡張症Up to Date, 南江堂, 2022
2. 小林義和, 松原肇: 抗真菌薬、抗ウイルス薬、抗寄生虫薬. 病気と薬2021, 薬局 増刊号72(4): pp1804-1841, 南山堂, 2021
3. 小林義和, 松原肇: 抗真菌薬、抗ウイルス薬、抗寄生虫薬. 病気と薬2020, 薬局 増刊号71(4): pp1814-1848, 南山堂, 2020
4. 小林義和, 篠崎公一. 薬物血中濃度の理解と応用. 日本化学療法学会雑誌. 2019; 67(3): 368-375.
5. 小林義和, 松原肇: 抗真菌薬、抗ウイルス薬、抗寄生虫薬. 病気と薬2018, 薬局 増刊号69(4): pp1798-1829, 南山堂, 2018
6. 小林義和, 松原肇: 抗真菌薬、抗ウイルス薬、抗寄生虫薬. 病気と薬2017, 薬局 増刊号68(4): pp1786-1817, 南山堂, 2017
7. 小林義和, 松原肇: 抗真菌薬、抗ウイルス薬、抗寄生虫薬. 病気と薬2016, 薬局 増刊号67(4): pp1616-1633, 南山堂, 2016
【学会発表】
1. 小林義和, 朝倉崇徳, 鈴木雄介: 北里大学薬学部におけるフィジカルアセスメント実習. 第7回日本薬学教育学会大会. 2022年8月20日
2. 増澤啓太, 中山莊平, 野村実由, 黒沼智, 竹内修, 松坂雅子, 小林義和, 寺井秀樹, 鈴木幸男, 鈴木雄介: T細胞分画測定による肺癌化学療法の効果予測. 第62回日本呼吸器学会学術講演会. 2022年4月22日
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